| Product Name | Anti-PAIP2 (clone AT1C12) |
|---|---|
| Description | PAIP2 (Poly(A)-binding protein-interacting protein 2) is a 127 amino acid protein. PAIP binds to the polyadenylate-binding protein (PABP). There are two PAIP proteins called PAIP1 and PAIP2. PAIP2 acts as a repressor in the regulation of translation initiation of poly(A)-containing mRNAs. and Paip1 stimulates translation. PAIP2 contains two binding sites for PABP, one encompassing a 16-amino-acid stretch located in the C terminus and a second encompassing a larger central region. |
| Synonyms | PAIP2A, PABP- interacting protein 2, HSPC218, Poly(A)-binding protein-interacting protein 2 poly(A) binding protein interacting protein 2. |
| Host | Mouse |
| Clone | AT1C12. Anti-human PAIP2 mAb, clone AT1C12, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PAIP2 protein. |
| Immunogen | Recombinant human PAIP2 (1-127aa) purified from E. coli |
| Isotype | IgG2b |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Khaleghpour, K., et al. (2001) Mol Cell Biol 7: 205-216Khaleghpour, K., et al. (2001) Cell Biol 21: 5200-5213vitkin, Y.V., et al. (2001) RNA 7: 1743-1752 |
| Supplier | ARP |
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