Anti-PPIF (Cyclophilin F) (clone AT1F5)

Antibodies, Monoclonal Antibodies
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Product Name Anti-PPIF (Cyclophilin F) (clone AT1F5)
Description Cyclophilin F (also known as Peptidylprolyl isomerase F, PPIF) is a member of peptidyl-prolyl cis-transisomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
Reactivity Human
Applications Dot blot, ELISA, IHC, WB
Clone AT1F5. Anti-human PPIF mAb, clone AT1F5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPIF protein.
Concentration 0.1 mg/ml
Form Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide.
Species Mouse
Host Mouse
Isotype K, IgG2b
Immunogen Recombinant human PPIF (30-207aa) purified from E. coli
Interest Fields Enzymes & Proteases
NCBI Number NP_005720
References Bowles kR, et al., (2000) Genomics 67(2):109-127 Bergsma DJ, et al., (1991) J Biol Chem 266(34):23204-23214
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Synonyms Peptidylprolyl isomerase F, CYP3, Cyp-D, PPIF, Peptidylprolyl isomerase F Cyclophilin 3, Cyclophilin D, Cyclophilin F, Cyp D, CYP3, CypD, hCyP3, Peptidylprolyl isomerase F (cyclophilin F), Peptidyl prolyl cis trans isomerase, mitochondral, Peptidylprolyl isomerase F, PPIase, Rotamase.
Working Dilutions Optimal dilution should be performed by user.

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