| Product Name | Anti-PPIF (Cyclophilin F) (clone AT1F5) |
|---|---|
| Description | Cyclophilin F (also known as Peptidylprolyl isomerase F, PPIF) is a member of peptidyl-prolyl cis-transisomerase family. They are highly-conserved cytoplasmic enzymes that accelerate protein folding. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death. |
| Synonyms | Peptidylprolyl isomerase F, CYP3, Cyp-D, PPIF, Peptidylprolyl isomerase F Cyclophilin 3, Cyclophilin D, Cyclophilin F, Cyp D, CYP3, CypD, hCyP3, Peptidylprolyl isomerase F (cyclophilin F), Peptidyl prolyl cis trans isomerase, mitochondral, Peptidylprolyl isomerase F, PPIase, Rotamase. |
| Host | Mouse |
| Clone | AT1F5. Anti-human PPIF mAb, clone AT1F5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human PPIF protein. |
| Immunogen | Recombinant human PPIF (30-207aa) purified from E. coli |
| Isotype | K,IgG2b |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC, WB, Dot Blot |
| Form | Purified, in Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Bowles kR, et al., (2000) Genomics 67(2):109-127 Bergsma DJ, et al., (1991) J Biol Chem 266(34):23204-23214 |
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