Anti-Progesterone Receptor (Marker of Progestin Dependence), Monoclonal Antibody
| Product Name | Anti-Progesterone Receptor (Marker of Progestin Dependence), Monoclonal Antibody |
|---|---|
| Description | This monoclonal antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa). Expression of PgR has been suggested to reflect a intact estrogen regulatory machinery and therefore, predict better clinical response to endocrine therapy than ER alone. It is excellent for immunohistochemical staining of formalin/paraffin tissues. |
| Synonyms | NR3C3, Nuclear receptor subfamily 3 group C member 3, PGR, PR, PRA, PRB, Progesterone receptor form A, Progesterone receptor form B |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | PR484 |
| Immunogen | Recombinant human Progesterone Receptor protein |
| Isotype | IgG1, kappa |
| Reactivity | Human |
| Applications | IHC |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 5241 |
| Uniprot | P06401 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Press M, et al. Steroids. 2002 Aug; 67(9):799-813.Mote P, et al. J Clin Pathol., 2001; 54: 624-630 |
| Supplier | ARP |
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