Anti-PSA (KLK3) (Hu) from Mouse (HAM18)

Category: Antibodies
Catalog
DIA-PSA
(Ships in 5-10 business days)

Questions? Contact us

Call (800) 832-2611

arp-guarantee
- +
$0.00
More Information
Product Name Anti-PSA (KLK3) (Hu) from Mouse (HAM18)
Description

HAM18 has been developed for detection of prostate specific antigen (PSA) in routine formalin-fixed paraffin-embedded prostate tissue specimen to be used in brightfield immunohistochemistry but also for multicolor immunofluorescence. HAM18 has been tested for sensitivity, specificity and prognostic significance on more than 20.000 tissues. Accordingly, HAM18 stands for be- ing the best validated anti-PSA clone. For details review www.PSA-antibody.com.

Prostate Cancer is the most common cancer in men and PSA is the most important target for management of patients diag- nosed with prostate cancer. PSA is a protease exclusively produced in prostate epithelial cells and secreted into the seminal flu- id. Moreover, PSA reaches the blood stream and PSA levels have been shown to be proportional to quantity of prostate epitheli- al cells. Therefore serum analysis has developed the most commonly used method to detect PSA for prostate cancer prevention and to monitor response to therapy. Moreover, PSA immunohistochemistry is an important and common method for routine pathological diagnosis since it allows analysis of cellular expression profiles in prostate cancer.

In diagnostic routine, PSA (HAM18) immunohistochemistry can be used in the following applications

  • Carcinoma of unknown origin: Rule out origin from a prostate cancer.

  • Bladder tumor of male patients without unequivocal urothelial precursor lesion suggesting urothelial origin: Rule out origin from a prostate cancer.

  • Advanced high-grade prostate cancer with rather low serum PSA levels: Low PSA expression in poorly differentiated cancer suggest that serum PSA levels may “underestimate” total tumor mass of the patient.

Host Mouse
Clone HAM18
Immunogen Recombinant peptide
Isotype IgG1, kappa
Specificity PSA (KLK3)
Reactivity Human
Applications IHC
Form Lyophilized, from PBS with 2% BSA, 0.05% NaN3,
pH 7.4. Antibody purified from culture supernatant.
Reconstitution DIA-PSA restore to 100 μl. Reconstitute with sterile distilled water by gentle shaking for 10 minutes
Storage Store the lyophilized antibody at 2-8°C. For long term storage freeze at -20°C, thus the antibody is stable for at least one year. As reconstituted liquid store at 2-8°C short term (several weeks). Avoid repeated freeze / thaw cycles.
Notes RUO
Supplier Dianova GmbH

All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.