| Product Name | Anti-RAP2B (clone AT62D9) |
|---|---|
| Description | RAP2B is 183 amino acid protein. It belongs to the Ras-related protein family. RAP2B is small GTP-binding protein which cycles between a GDP-bound inactive and a GTP-bound active form. RAP2B is involved in EGFR and CHRM3 signaling pathways through stimulation of PLCE1. It may be associated with cytoskeletal rearrangements and regulate cell spreading through activation of the effector TNIK and regulate membrane vesiculation in red blood cells. |
| Synonyms | Ras-related protein Rap-2b, RAP2B, member of RAS oncogene family |
| Host | Mouse |
| Clone | Anti-human RAP2B mAb, clone AT62D9, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human Rap2b protein. |
| Immunogen | Recombinant human RAP2B (1-183aa) purified from E. coli |
| Isotype | IgG1,K |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Evellin. S., et al. (2002) J Biol Chem 277: 16805-16813Stope. M.B., et al. (2004) Mol Cell Biol 24: 4664-4676 Greco. F., et al. (2006) Biochim Biophys Acta 1763: 330-335 |
| Supplier | ARP |
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