| Product Name | Anti-Rh blood group-related antigen Monoclonal Antibody |
|---|---|
| Description | Mouse monoclonal antibody to human Rh blood group-related antigen Affinity purified. Rh is the most complex of the human blood group systems, with 45 well-defined antigens. BRIC 69 and other antibodies of similar specificity (such as LICR/LON R6A) have been used in immunoprecipitation experiments to identify transmembrane proteins of Mr 31kDa and Mr 35-52kDa on normal erythrocytes which are not found in Rhnull erythrocytes. The sequence of cDNA encoding one of the 30k proteins has been cloned2,. |
| Synonyms | Rh blood group antigen, LICR protein, LON protein, R6A protein |
| Clonality | Monoclonal |
| Clone | BRIC 69 |
| Immunogen | Blood group related RH Antigen. BRIC 69 was made in response to human erythrocytes. |
| Isotype | Mouse IgG1 kappa light chain |
| Reactivity | Human |
| Applications | FC, ICC, IP, WB |
| Form | Affinity purified, in 0.1 M glycine buffer, 1 M Tris buffer, pH 7.4, sterile filtered |
| Storage | 2-8C for immediate use, or at -2°C (aliquot) |
| References | 1. Avent, ND., et al. (1988) Biochem J. 251: 499-505 2. Avent, ND., et al. (1990) Biochem J. 271: 821-825 3. Cherif-Zahar, B. et al. (1990) Proc. Natl. Acad. Sci (USA) 87: 6243-6247 4. Gardner, B. et al. (1991) Transf. Med. 1: 77-85 5. Chester MA et al (ed) (1990) Proceedings of the second international workshop and symposium on monoclonal antibodies against human red blood cells and related antigens, Lund 1990. |
| Supplier | ARP |
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