| Product Name | Anti-RSV Phosphoprotein VP32 Monoclonal Antibody |
|---|---|
| Description | This antibody reacts with the phosphoprotein from both human RS virus subgroups A and B as well as the phosphoprotein of bovine RS virus. The antibody is not reactive with the phosphoprotein of other member of Pneumovirus genus (specifically, pneumonia virus of mice). On the basis of the reactivity of this antibody and the 4-14 antibody (cat number: 151851) against the VP32 protein (by immunoblot and immunofluorescence) the existence of two antigenic types of human RS virus was identified (Gimenez et al., 1986). The phosphoprotein is located within the virion nucleocapsid. The phosphoprotein of RS virus subgroup A is slightly larger than the phosphoprotein of RS virus subgroup B. This difference in molecular weight was demonstrated by immunoblot using this antibody (Gimenez et al., 1986). This antibody is useful for the diagnosis of RS virus infection since the phosphoprotein is abundant which makes the detection assays using this antibody highly sensitive. |
| Host | Mouse |
| Clone | 3/5/2018 |
| Immunogen | The immunogen was gradient-purified RSN-2 virus (subgroup B) that was then treated with 0.1% SDS at 100°C for 2 min. The procedure used to produce this antibody is described in Gimenez et al. (1984). |
| Isotype | IgG1 kappa |
| Reactivity | Virus |
| Applications | ELISA, IF, IHC, WB |
| Background |
This antibody reacts with the phosphoprotein from both human RS virus subgroups A and B as well as the phosphoprotein of bovine RS virus. The antibody is not reactive with the phosphoprotein of other member of Pneumovirus genus (specifically, pneumonia virus of mice). On the basis of the reactivity of this antibody and the 4-14 antibody (cat number: 151851) against the VP32 protein (by immunoblot and immunofluorescence) the existence of two antigenic types of human RS virus was identified (Gimenez et al., 1986). The phosphoprotein is located within the virion nucleocapsid. The phosphoprotein of RS virus subgroup A is slightly larger than the phosphoprotein of RS virus subgroup B. This difference in molecular weight was demonstrated by immunoblot using this antibody (Gimenez et al., 1986). This antibody is useful for the diagnosis of RS virus infection since the phosphoprotein is abundant which makes the detection assays using this antibody highly sensitive. |
| Supplier | Vertebrate Antibodies Limited |
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