Anti-Ryanodine Receptor Monoclonal Antibody, FITC

Antibodies, Monoclonal Antibodies
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Product Name Anti-Ryanodine Receptor Monoclonal Antibody, FITC
Description Mouse monoclonal antibody to Ryanodine Receptor-FITC conjugate is useful in the area of the neurosciences with particular application in aging studies and Alzheimer research.
Reactivity Human, Mouse and bovine cells/tissues, Pig, Rabbit
Applications FC, IF
Clone RYR.1
Conjugate FITC
Form FITC conjugate, in 10mM sodium phosphate, 150mM NaCl, 0.01% NaN3, pH 7.5
Isotype Mouse IgG2b
Immunogen Short synthetic polypeptide which recognizes the C-terminus cytoplasmic domain of ryanodine receptor
Intended Use For Research Use Only
Specificity This antibody reacts with ryanodine receptor (a homotetramer with subunit molecular weight ca. 500 kDa) isolated from variety of cell types (e.g. skeletal muscle, cardiac muscle, brain tissues, lymphocytes, macrophages, granulocytes, fibroblasts, epithelial and endothelial cells). Ryanodine receptors have been shown to play critical roles in the intracellular Ca2+ signaling occurring during cell activation in muscle cells and non-muscle cells.
Storage 2-8C for immediate use, or at -20C (aliquot)
Synonyms Ryanodine Receptor antibody, anti Ryanodine Receptor antibody, Ryanodine Receptor
Working Dilutions Optimal dilution should be performed by user.

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