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|Product Name||Anti-SAR1B (clone AT1C7)|
|Description||SAR1B (GTP-binding protein SAR1b) is 198 amino acid protein. SAR1B is involved in transport from the endoplasmic reticulum to the Golgi apparatus. This protein is activated by the guanine nucleotide exchange factor PREB. It is involved in the selection of the protein cargo and the assembly of the COPII coat complex. Mutations in the SAR1B gene are associated with CMRD which is autosomal recessive disorder of severe fat malabsorption.|
|Applications||Dot blot, ELISA, WB|
|Clone||AT1C7. Anti-human SAR1B mAb, clone AT1C7, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SAR1B protein.|
|Form||Purified, in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide.|
|Immunogen||Recombinant human SAR1B (1-198aa) purified from E. coli|
|Interest Fields||Signal Transduction|
|References||Jones, B., et al. (2003) Nat Genet 34(1): 29€“31Annesi, G., et al. (2007) Clin Genet 71(3): 288-9Treepongkaruna, S., et al. (2009) J Pediatr Gastroenterol Nutr 48(3): 370-3|
|Storage||Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.|
|Synonyms||GTP-binding protein SAR1b, ANDD, CMRD, GTBPB, SARA2|
|Working Dilutions||Optimal dilution should be performed by user.|
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