Anti-SAR1B (clone AT1C7)

Antibodies, Monoclonal Antibodies
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Product Name Anti-SAR1B (clone AT1C7)
Description SAR1B (GTP-binding protein SAR1b) is 198 amino acid protein. SAR1B is involved in transport from the endoplasmic reticulum to the Golgi apparatus. This protein is activated by the guanine nucleotide exchange factor PREB. It is involved in the selection of the protein cargo and the assembly of the COPII coat complex. Mutations in the SAR1B gene are associated with CMRD which is autosomal recessive disorder of severe fat malabsorption.
Reactivity Human
Applications Dot blot, ELISA, WB
Clone AT1C7. Anti-human SAR1B mAb, clone AT1C7, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SAR1B protein.
Concentration 0.1 mg/ml
Form Purified, in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide.
Species Mouse
Host Mouse
Isotype IgG1, K
Immunogen Recombinant human SAR1B (1-198aa) purified from E. coli
Interest Fields Signal Transduction
NCBI Number NP_057187
References Jones, B., et al. (2003) Nat Genet 34(1): 29€“31Annesi, G., et al. (2007) Clin Genet 71(3): 288-9Treepongkaruna, S., et al. (2009) J Pediatr Gastroenterol Nutr 48(3): 370-3
Storage Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Synonyms GTP-binding protein SAR1b, ANDD, CMRD, GTBPB, SARA2
Working Dilutions Optimal dilution should be performed by user.

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