| Product Name | Anti-SNTA1 (clone AT1E1) |
|---|---|
| Description | SNTA1 (Syntrophin alpha 1) is 505 amino acid protein. SNTA1 is adapter protein that binds to and probably organizes the subcellular localization of a variety of membrane proteins. It may link various receptors to the actin cytoskeleton and the extracellular matrix via the dystrophin glycoprotein complex. SNTA1 plays an important role in synapse formation and in the organization of UTRN and acetylcholine receptors at the neuromuscular synapse. Defects of SNTA1 are the cause of long QT syndrome type 12 (LQT12). |
| Synonyms | Syntrophin, alpha 1, dJ1187J4.5, LQT12, SNT1, TACIP1 |
| Host | Mouse |
| Clone | AT1E1. Anti-human SNTA1 mAb, clone AT1E1, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SNTA1 protein. |
| Immunogen | Recombinant human SNTA1 (1-505aa) purified from E. coli |
| Isotype | K,IgG2b |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Purified, in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Wu, G., et al. (2008) Circ Arrhythm Electrophysiol 1: 193-201Ahn, A.H., et al. (1996) J Biol Chem 271(5): 2724€“30 Yang, B., et al (1995) J Biol Chem 270(10): 4975€“8 |
| Supplier | ARP |
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