| Product Name | Anti-SORD (clone AT10F4) |
|---|---|
| Description | SORD, also known as sorbitol dehydrogenase, is a 357 amino acid protein of the zinc-containing alcohol dehydrogenase family. It is widely expressed with highest expression in kidney, lens of the eye and malignant prostate tissue. SORD enzymatically catalyzes the zinc-dependent interconversion of polyols, such as sorbitol and xylitol, to their respective ketoses. SORD deficiency may be associated with diabetic complications such as cataracts and microvascular problems. |
| Synonyms | Sorbitol dehydrogenase L iditol 2 dehydrogenase, SDH, SORD, SORD 1, SORD1 |
| Host | Mouse |
| Clone | Anti-human SORD mAb, clone AT10F4, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SORD protein. |
| Immunogen | Recombinant human SORD (1-357aa) purified from E. coli |
| Isotype | IgG1,K |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Frenette. G., et al. (2006) J Androl 27: 233-239 Szabo. Z., et al. (2010) Oncol Rep 23: 1233-1239Lanaspa. M.A., et al. (2009) J Biol Chem 284: 19974-19981 |
| Supplier | ARP |
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