| Product Name | Anti-SPATA25 Monoclonal Antibody |
|---|---|
| Description | SPATA25 (spermatogenesis-associated protein 25), also known as TSG23 (testis-specific gene 23 protein), is a 227 amino acid single-pass membrane protein that is thought to play a role in spermatogenesis. Predominantly expressed in testis, SPATA25 is found at 60-fold higher levels in adult testis than fetal testis. The gene encoding SPATA25 maps to human chromosome 20q13.12 and mouse chromosome 2 H3. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought to be important for seminal production and may be potential targets for male contraception. |
| Synonyms | Testis-specific gene 23 protein |
| Host | Mouse |
| Clone | Z37P3H11*B2 |
| Immunogen | Peptide Sequence – LVRSKRGQP |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Background | SPATA25 (spermatogenesis-associated protein 25), also known as TSG23 (testis-specific gene 23 protein), is a 227 amino acid single-pass membrane protein that is thought to play a role in spermatogenesis. Predominantly expressed in testis, SPATA25 is found at 60-fold higher levels in adult testis than fetal testis. The gene encoding SPATA25 maps to human chromosome 20q13.12 and mouse chromosome 2 H3. Comprising approximately 2% of the human genome, chromosome 20 contains nearly 63 million bases that encode over 600 genes, some of which are associated with Creutzfeldt-Jakob disease, amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome. Additionally, chromosome 20 contains a region with numerous genes which are thought to be important for seminal production and may be potential targets for male contraception. |
| Supplier | Vertebrate Antibodies Limited |
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