| Product Name | Anti-SSR4 (clone AT26G5) |
|---|---|
| Description | SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus. |
| Synonyms | Translocon-associated protein subunit delta, TRAPD |
| Host | Mouse |
| Clone | Anti-human SSR4 mAb, clone AT26G5, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human SSR4 protein. |
| Immunogen | Recombinant human SSR4 (24-144aa) purified from E. coli |
| Isotype | IgG1,K |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Liquid. Supplied in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.02% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Brenner V., et al. (1997) Genomics 44 (1): 8-14Holthuis JC., et al. (1996) J Biol Chem 312 ( Pt 1) (Pt 1): 205-13Entrez Gene: SSR4 signal sequence receptor, delta |
| Supplier | ARP |
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