| Product Name | Anti-TNFRSF18 (soluble form) Monoclonal Antibody |
|---|---|
| Description | TNFRSF18 is a type I transmembrane protein with homology to members of divergent costimulatory molecules in the TNFRSF. To date three isoforms of TNFRSF18 have been identified, including one soluble form that lacks a transmembrane domain. According to homology of the cytoplasmic domain, TNFRSF18 and other three TNFRSF members (4–1BB, CD27, and OX40) probably constitute a new subfamily as divergent costimulators. TNFRSF18 and the other subfamily members bind TRAF molecules and activate NF-KB. |
| Synonyms | Tumor Necrosis Factor Receptor Superfamily Member 18, Glucocorticoid-Induced TNFR-Related Protein, Activation-Inducible TNFR Family Receptor, AITR, GITR, TNF Receptor Superfamily Activation-Inducible Protein, CD357 Antigen, GITR-D, CD357 |
| Host | Mouse |
| Clone | T10P2H9*B9 |
| Immunogen | Ovalbumin conjugated peptide - PWQQKWVQE |
| Isotype | IgG1 kappa |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Background | TNFRSF18 is a type I transmembrane protein with homology to members of divergent costimulatory molecules in the TNFRSF. To date three isoforms of TNFRSF18 have been identified, including one soluble form that lacks a transmembrane domain. According to homology of the cytoplasmic domain, TNFRSF18 and other three TNFRSF members (4–1BB, CD27, and OX40) probably constitute a new subfamily as divergent costimulators. TNFRSF18 and the other subfamily members bind TRAF molecules and activate NF-KB. |
| Supplier | Vertebrate Antibodies Limited |
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