| Product Name | Anti-TNNI1 (clone AT36E7) |
|---|---|
| Description | Troponin I, slow skeletal muscle, also known as TNNI1, belongs to the troponin I family. The troponin I subfamily contains three genes: TNNI-skeletal-fast-twitch, TNNI-skeletal-slow-twitch, and TNNI-cardiac. The TNNI-fast and TNNI-slow genes are expressed in fast-twitch and slow-twitch skeletal muscle fibers, respectively, while the TNNI-cardiac gene is expressed exclusively in cardiac muscle tissue. TNNI1 is the inhibitory subunit; blocking actin-myosin interactions and thereby mediating striated muscle relaxation. |
| Synonyms | Troponin I, slow skeletal muscle, DKFZp451O223, SSTNI, TNN1 |
| Host | Mouse |
| Clone | AT36E7. Anti-human TNNI1 mAb, clone AT36E7, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human TNNI1 protein. |
| Immunogen | Recombinant human TNNI1 (1-187aa) purified from E. coli |
| Isotype | IgG2b.k |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB, Dot Blot |
| Form | Purified, in Phosphate-Buffered Saline (pH 7.4) containing 10% Glycerol, 0.01% Sodium Azide. |
| Storage | Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles. |
| References | Hunkeler NM, Kullman J, Murphy AM (1991). Circ. Res. 69 (5): 1409€“14.Bhavsar PK, Dhoot GK, Cumming DV, et al. (1992). FEBS Lett. 292 (1-2): 5€“8.Westfall MV, Borton AR (2003). J. Biol. Chem. 278 (36): 33694€“700. |
| Supplier | ARP |
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