Anti-Vimentin (Mesenchymal Cell Marker), Monoclonal Antibody
| Product Name | Anti-Vimentin (Mesenchymal Cell Marker), Monoclonal Antibody |
|---|---|
| Description | This monoclonal antibody reacts with a 58kDa protein identified as vimentin. It shows no cross-reaction with other closely related intermediate filament proteins (IFP_Ûªs) such as desmin, keratin, neurofilament, and glial fibrillary acid protein._Anti-vimentin alone is of limited value as a diagnostic tool; however, when used in panels with other antibodies, it is useful for the sub-classification of a given tumor. Expression of vimentin, when used in conjunction with anti-keratin, is helpful when distinguishing melanomas from undifferentiated carcinomas and large cell lymphomas. All melanomas and Schwannomas react strongly with anti-vimentin. It labels a variety of mesenchymal cells, including melanocytes, lymphocytes, endothelial cells, and fibroblasts. Non-reactivity of anti-vimentin is often considered more useful than its positive reactivity, since there are a few tumors that do not contain vimentin, e.g. hepatoma and seminoma. Anti-vimentin is also useful as a tissue process control reagent. |
| Synonyms | VIM |
| Host | Mouse |
| Clonality | Monoclonal |
| Clone | SPM576 |
| Immunogen | Human vimentin recombinant protein |
| Isotype | IgG1 |
| Reactivity | Gallus, Bovine, Canine, Feline, Goat, Human, Porcine |
| Applications | FC, IF, IHC, WB |
| Form | 200ug/ml of Ab purified from Bioreactor Concentrate by Protein A/G. Prepared in 10mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0mg/ml. |
| Gene Id | 7431 |
| Uniprot | P08670 |
| Storage | Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required. |
| References | Osborn M et. al. European Journal of Cell Biology. 1984; 34:137-143 |
| Supplier | ARP |
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