| Product Name | APBA2BP Polyclonal Antibody |
|---|---|
| Description | The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is NECAB1. |
| Synonyms | NECAB3; APBA2BP; NIP1; SYTIP2; XB51; N-terminal EF-hand calcium-binding protein 3; Amyloid beta A4 protein-binding family A member 2-binding protein; Nek2-interacting protein 1; Neuronal calcium-binding protein 3; X11L-binding protein 51 |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the C-terminal region of human APBA2BP |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Uniprot | Q96P71 |
| Background | The protein encoded by this gene interacts with the amino-terminal domain of the neuron-specific X11-like protein (X11L), inhibits the association of X11L with amyloid precursor protein through a non-competitive mechanism, and abolishes the suppression of beta-amyloid production by X11L. This protein, together with X11L, may play an important role in the regulatory system of amyloid precursor protein metabolism and beta-amyloid generation. The protein is phosphorylated by NIMA-related expressed kinase 2, and localizes to the Golgi apparatus. Multiple transcript variants encoding different isoforms have been found for this gene. NECAB3 (N-Terminal EF-Hand Calcium Binding Protein 3) is a Protein Coding gene. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is NECAB1. |
| Supplier | Elabscience |
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