APEH Antibody

Category: Antibodies
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CSB-PA194613
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Product Name APEH Antibody
Description Rabbit polyclonal antibody to APEH
Synonyms AARE antibody; ACPH antibody; ACPH_HUMAN antibody; Acyl peptide hydrolase antibody; Acyl-peptide hydrolase antibody; Acylamino acid releasing enzyme antibody; Acylamino-acid-releasing enzyme antibody; Acylaminoacyl peptidase antibody; Acylaminoacyl-peptidase antibody; APEH antibody; APH antibody; N acylaminoacyl peptide hydrolase antibody; OPH antibody; Oxidized protein hydrolase antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Synthetic peptide of human APEH
Isotype IgG
Target APEH
Reactivity Human, Mouse, Rat
Applications ELISA, IHC, WB
Form Liquid
Diluent Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Uniprot P13798
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background This gene encodes the enzyme acylpeptide hydrolase, which catalyzes the hydrolysis of the terminal acetylated amino acid preferentially from small acetylated peptides. The acetyl amino acid formed by this hydrolase is further processed to acetate and a free amino acid by an aminoacylase. This gene is located within the same region of chromosome 3 (3p21) as the aminoacylase gene, and deletions at this locus are also associated with a decrease in aminoacylase activity. The acylpeptide hydrolase is a homotetrameric protein of 300 kDa with each subunit consisting of 732 amino acid residues. It can play an important role in destroying oxidatively damaged proteins in living cells. Deletions of this gene locus are found in various types of carcinomas, including small cell lung carcinoma and renal cell carcinoma.
Supplier Cusabio

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