| Product Name | APLP2 (Ab-755) Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to APLP2 (Ab-755) |
| Synonyms | amyloid beta (A4) precursor like protein 2 antibody; Amyloid like protein 2 antibody; Amyloid precursor protein homolog HSD 2 antibody; amyloid precursor protein homolog HSD2 antibody; Amyloid protein homolog antibody; Amyloid-like protein 2 antibody; APLP-2 antibody; Aplp2 antibody; APLP2_HUMAN antibody; APPH antibody; APPL2 antibody; CDEBP antibody; CDEI box binding protein antibody; CDEI box-binding protein antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized non-phosphopeptide derived from human APLP2 around the phosphorylation site of tyrosine 755 (P-T-Y(p)-K-Y). |
| Isotype | IgG |
| Target | APLP2 |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | Q06481 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts By similarity. Sprecher C.A., Biochemistry 32:4481-4486(1993). Wasco W., Nat. Genet. 5:95-99(1993). von der Kammer H., DNA Cell Biol. 13:1137-1143(1994). |
| Supplier | Cusabio |
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