| Product Name | APOBEC4, 1-367aa, Human |
|---|---|
| Description | The APOBEC4 is a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in Mrna editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. Recombinant human APOBEC4 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Synonyms | C1orf169 |
| Host | E. coli |
| Molecular Weight | 15.4 kDa (140aa) confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMEPIYEE YLANHGTIVK PYYWLSFSLD CSNCPYHIRT GEEARVSLTE FCQIFGFPYG TTFPQTKHLT FYELKTSSGS LVQKGHASSC TGNYIHPESM LFEMNGYLDS AIYNNDSIRH IILYSNNSPC NEANHCCISK MYNFLITYPG ITLSIYFSQL YHTEMDFPAS AWNREALRSL ASLWPRVVLS PISGGIWHSV LHSFISGVSG SHVFQPILTG RALADRHNAY EINAITGVKP YFTDVLLQTK RNPNTKAQEA LESYPLNNAF PGQFFQMPSG QLQPNLPPDL RAPVVFVLVP LRDLPPMHMG QNPNKPRNIV RHLNMPQMSF QETKDLGRLP TGRSVEIVEI TEQFASSKEA DEKKKKKGKK |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol |
| Concentration | 0.25 mg/ml (determined by BCA assay) |
| Purity | > 85% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Prochnow,C., et al. (2009) Sci. China, C, Life Sci. 52 (10), 893-902 Rogozin,I.B., et al. (2005) Cell Cycle 4 (9), 1281-1285 |
| Background | The APOBEC4 is a member of the AID/APOBEC family of polynucleotide (deoxy)cytidine deaminases, which convert cytidine to uridine. Other AID/APOBEC family members are involved in Mrna editing, somatic hypermutation and recombination of immunoglobulin genes, and innate immunity to retroviral infection. Recombinant human APOBEC4 protein, fused to His-tag at N-terminus, was expressed in E.coli. |
| Supplier | ARP |
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