| Product Name | ApoC-III Polyclonal Antibody |
|---|---|
| Description | Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.APOC3 (Apolipoprotein C3) is a Protein Coding gene. Diseases associated with APOC3 include Apolipoprotein C-Iii Deficiency and Hyperalphalipoproteinemia. Among its related pathways are Metabolism of fat-soluble vitamins and Statin Pathway. GO annotations related to this gene include lipid binding and cholesterol binding. |
| Synonyms | APOC3, Apolipoprotein C-III, Apo-CIII, ApoC-III, Apolipoprotein C3 |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the C-terminal region of human ApoC-III. |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Uniprot | P02656 |
| Background | Apolipoprotein C-III is a very low density lipoprotein (VLDL) protein. APOC3 inhibits lipoprotein lipase and hepatic lipase; it is thought to delay catabolism of triglyceride-rich particles. The APOA1, APOC3 and APOA4 genes are closely linked in both rat and human genomes. The A-I and A-IV genes are transcribed from the same strand, while the A-1 and C-III genes are convergently transcribed. An increase in apoC-III levels induces the development of hypertriglyceridemia.APOC3 (Apolipoprotein C3) is a Protein Coding gene. Diseases associated with APOC3 include Apolipoprotein C-Iii Deficiency and Hyperalphalipoproteinemia. Among its related pathways are Metabolism of fat-soluble vitamins and Statin Pathway. GO annotations related to this gene include lipid binding and cholesterol binding. |
| Supplier | Elabscience |
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