| Product Name | ARG1 Monoclonal Antibody |
|---|---|
| Description | Arginase-1 (Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical_marker_of hepatocellular differentiation in fine needle aspiration cytology and a marker_of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins.It can exsit as a homotrimer and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2,which is critical for pathogen control.. ARG1 is a novel biomarker of post-stroke immune suppression(2016). |
| Synonyms | Arginase 1,liver Arginase,Liver type arginase |
| Host | Mouse |
| Clone | 700 |
| Immunogen | Fusion protein of ARG1 |
| Isotype | IgG1 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P07824 |
| Background | Arginase-1 (Liver arginase) belongs to the arginase family. ARG1 is a novel immunohistochemical_marker_of hepatocellular differentiation in fine needle aspiration cytology and a marker_of hepatocytes and hepatocellular neoplasms. ARG1 is closely associated with alternative macrophage activation and ARG1 has been shown to protectmotor neurons from trophic factor deprivation and allow sensory neurons to overcome neurite outgrowth inhibition by myelin proteins.It can exsit as a homotrimer and it has 3 isoforms produced by alternative splicing.Defects in ARG1 are the cause of argininemia (ARGIN). Deletion or TNF-mediated restriction of ARG1 unleashes the production of NO by NOS2,which is critical for pathogen control.. ARG1 is a novel biomarker of post-stroke immune suppression(2016). |
| Supplier | Elabscience |
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