| Product Name | [Arg8]-Vasopressin |
|---|---|
| Description |
[Arg8]-Vasopressin is an antidiuretic hormone of hypothalamic origin found in most mammalian species, which is an endogenous agonist for all three subtypes of vasopressin receptor, V1A, V1B and V2. [Arg8]-vasopressin is an important regulator of fluid and electrolyte homeostasis through its anti-diuretic action on the kidney, and is involved in vasodepression and also acts as a neurotransmitter at synapses in the brain where it is involved in cognitive functions including memory. |
| Synonyms | Argipressin, AVP, Arginine-8-vasopressin |
| Molecular Weight | 1084.23 Da |
| Target | Vasopressin receptors |
| Amino Acid Sequence | CYFQNCPRG-NH2 |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Cas Number | 113-79-1 |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: Disulfide bridge between cysteines 1 and 6, C-terminal amide |
| References |
Thibonnier et al (1991) Multiple signaling pathways of V1-vascular vasopressin receptors of A7r5 cells. Endocrinology 129(6) 2845 PMID: 1659517Mihara et al (1999) [Arg8]-vasopressin-induced increase in intracellular Ca2+ concentration in cultured rat hippocampal neurons. Brain Res Bull. 49(5) 343 PMID: 10452354Moriya et al (2012) Vasopressin-induced intracellular Ca²º concentration responses in non-neuronal cells of the rat dorsal root ganglion. Brain Res. 1483 1 PMID: 22975133 Related areasAll peptides >All vasopressin receptor modulators >All endocrinology research categories >All neuroscience research categories > |
| Supplier | Isca Biochemicals Limited |
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