| Product Name | ARHGEF11 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to ARHGEF11 |
| Synonyms | ARHGB_HUMAN antibody; ARHGEF 11 antibody; ARHGEF11 antibody; DKFZp667F1223 antibody; Glutamate transporter EAAT4 associated protein 48 antibody; GTRAP 48 antibody; GTRAP48 antibody; KIAA0380 antibody; OTTHUMP00000038716 antibody; OTTHUMP00000038717 antibody; PDZ RHOGEF antibody; PDZ-RhoGEF antibody; Rho guanine exchange factor (GEF) 11 antibody; Rho guanine nucleotide exchange factor (GEF) 11 antibody; Rho guanine nucleotide exchange factor 11 antibody; RhoA specific guanine nucleotide exchange factor antibody; RhoGEF glutamate transport modulator antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from N-terminal of human ARHGEF11. |
| Isotype | IgG |
| Target | ARHGEF11 |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | O15085 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13. Involved in neurotrophin-induced neurite outgrowth. Nagase T., DNA Res. 4:141-150(1997). Gregory S.G., Nature 441:315-321(2006). Ruemenapp U., FEBS Lett. 459:313-318(1999). |
| Supplier | Cusabio |
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