Product Name | ASCC1 Antibody |
---|---|
Description | Rabbit polyclonal antibody to ASCC1 |
Synonyms | Activating signal cointegrator 1 complex subunit 1 antibody; ASC-1 complex subunit p50 antibody; ASC1 complex subunit p50 antibody; ASC1p50 antibody; ASCC1 antibody; ASCC1_HUMAN antibody; CGI 18 antibody; RP11-150D20.4 antibody; Trip4 complex subunit p50 antibody |
Host | Rabbit |
Clonality | Polyclonal |
Conjugate | Unconjugated |
Immunogen | Fusion protein of human ASCC1 |
Isotype | IgG |
Target | ASCC1 |
Reactivity | Human, Mouse |
Applications | ELISA, IHC |
Form | Liquid |
Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Uniprot | Q8N9N2 |
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
Background | This gene encodes a subunit of the activating signal cointegrator 1 (ASC-1) complex. The ASC-1 complex is a transcriptional coactivator that plays an important role in gene transactivation by multiple transcription factors including activating protein 1 (AP-1), nuclear factor kappa-B (NF-kB) and serum response factor (SRF). The encoded protein contains an N-terminal KH-type RNA-binding motif which is required for AP-1 transactivation by the ASC-1 complex. Mutations in this gene are associated with Barrett esophagus and esophageal adenocarcinoma. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. |
Supplier | Cusabio |
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