| Product Name | ASPRV1, 191-326aa, Human |
|---|---|
| Description | ASPRV1, also known as MUNO, SASP and ASAPase, is a protein that contains 1 peptidase A2 domain. This protein is expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles and localized to membrane region. This protein undergoes autocleavage which is necessary for activation of the protein. Recombinant human ASPRV1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | Aspartic peptidase, retroviral-like 1, MUNO, SASP, SASPase, Taps |
| Host | E. coli |
| Molecular Weight | 11.5 kDa (104aa) confirmed by MALDI-TOF |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSSMGKGYY LKGKIGKVPV RFLVDSGAQV SVVHPNLWEE VTDGDLDTLQ PFENVVKVAN GAEMKILGVW DTAVSLGKLK LKAQFLVANA SAEEAIIGTD VLQDHNAILD FEHRTCTLKG KKFRLLPVGG SLEDEFDLE |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol, 2mM DTT |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Matsui,T., et al. (2011) EMBO Mol Med 3 (6), 320-333 Rhiemeier,V., et al. (2006) Am. J. Pathol. 168 (4), 1354-1364 |
| Background | ASPRV1, also known as MUNO, SASP and ASAPase, is a protein that contains 1 peptidase A2 domain. This protein is expressed primarily in the granular layer of the epidermis and inner root sheath of hair follicles and localized to membrane region. This protein undergoes autocleavage which is necessary for activation of the protein. Recombinant human ASPRV1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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