| Product Name | ATF3 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to ATF3 |
| Synonyms | Activating transcription factor 3 antibody; ATF3 antibody; ATF3_HUMAN antibody; ATF3deltaZip2 antibody; ATF3deltaZip2c antibody; ATF3deltaZip3 antibody; cAMP dependent transcription factor ATF3 antibody; cAMP-dependent transcription factor ATF-3 antibody; Cyclic AMP dependent transcription factor ATF3 antibody; Cyclic AMP-dependent transcription factor ATF-3 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from internal of human ATF3. |
| Isotype | IgG |
| Target | ATF3 |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | P18847 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Represses transcription from promoters with ATF sites. It may repress transcription by stabilizing the binding of inhibitory cofactors at the promoter. Isoform 2 activates transcription presumably by sequestering inhibitory cofactors away from the promoters. Chen B.P.C., J. Biol. Chem. 269:15819-15826(1994). Hai T., Genes Dev. 3:2083-2090(1989). Hillman R.T., Genome Biol. 5:RESEARCH008.1-RESEARCH008.16(2004). |
| Supplier | Cusabio |
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