| Product Name | ATP8A1 Antibody, Biotin conjugated |
|---|---|
| Description | Rabbit polyclonal antibody against ATP8A1 conjugated to Biotin. |
| Synonyms | ATP8A1 antibody; ATPIAPhospholipid-transporting ATPase IA antibody; EC 7.6.2.1 antibody; ATPase class I type 8A member 1 antibody; Chromaffin granule ATPase II antibody; P4-ATPase flippase complex alpha subunit ATP8A1 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Biotin |
| Immunogen | Recombinant human Phospholipid-transporting ATPase IA protein (448-545AA) |
| Isotype | IgG |
| Target | ATP8A1 |
| Reactivity | Human |
| Applications | ELISA |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q9Y2Q0 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Catalytic component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation seems also to be implicated in vesicle formation and in uptake of lipid signaling molecules. In vitro, its ATPase activity is selectively and stereospecifically stimulated by phosphatidylserine (PS). The flippase complex ATP8A1:TMEM30A seems to play a role in regulation of cell migration probably involving flippase-mediated translocation of phosphatidylethanolamine (PE) at the plasma membrane. Acts as aminophospholipid translocase at the plasma membrane in neuronal cells. |
| Supplier | Cusabio |
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