| Product Name | ATXN7L3 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to ATXN7L3 |
| Synonyms | AT7L3_HUMAN antibody; Ataxin 7 like 3 antibody; Ataxin 7 like protein 3 antibody; Ataxin-7-like protein 3 antibody; atxn7l3 antibody; SAGA associated factor 11 homolog antibody; SAGA-associated factor 11 homolog antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Recombinant human Ataxin-7-like protein 3 protein (51-347AA) |
| Isotype | IgG |
| Target | ATXN7L3 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | Preservative: 0.03% Proclin 300Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Uniprot | Q14CW9 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | Component of the transcription regulatory histone acetylation (HAT) complex SAGA, a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. Within the complex, it is required to recruit USP22 and ENY2 into the SAGA complex. |
| Supplier | Cusabio |
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