| Product Name | AURKAIP1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to AURKAIP1 |
| Synonyms | 28S ribosomal protein S38 antibody; AIP antibody; AKIP_HUMAN antibody; AURKA interacting protein antibody; AURKA-interacting protein antibody; AURKAIP 1 antibody; Aurkaip1 antibody; Aurora A kinase interacting protein antibody; Aurora kinase A interacting protein 1 antibody; Aurora kinase A-interacting protein antibody; FLJ20608 antibody; mitochondrial antibody; MRP-S38 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human AURKAIP1 |
| Isotype | IgG |
| Target | AURKAIP1 |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q9NWT8 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | AKIP (AURKA-interacting protein), also known as AURKAIP1 (aurora kinase A interacting protein 1) or AIP, is a 199 amino acid protein that localizes to the nucleus and is ubiquitously expressed, with highest levels present in testis, heart and skeletal muscle. Interacting specifically with ARK-1 (aurora kinase 1), AKIP functions to induce the proteasomal-dependent degradation of ARK-1, thereby acting as a negative regulator of ARK-1 activity. AKIP is encoded by a gene which maps to human chromosome 1, which spans 260 million base pairs, contains over 3,000 genes and comprises nearly 8% of the human genome. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, ParkinsonÕs disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma. |
| Supplier | Cusabio |
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