| Product Name | Aven Polyclonal Antibody |
|---|---|
| Description | Aven binds to both Bcl-x(L) and the caspase regulator Apaf-1,which can supported that Bcl-x(L) inhibits cell death at a late (postmitochondrial) step in the death pathway.Identified in a yeast two-hybrid screen,Aven inhibited the proteolytic activation of caspases in a cell-free extract and suppressed apoptosis induced by Apaf-1 plus caspase-9. Expressing highly in the testis, ovary, and thymus . |
| Synonyms | AVEN; Cell death regulator Aven |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the C-terminal region of human Aven |
| Isotype | IgG |
| Reactivity | Human, Primate |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide,0.5% BSA and 50% glycerol pH 7.4. |
| Uniprot | Q9NQS1 |
| Background | Aven binds to both Bcl-x(L) and the caspase regulator Apaf-1,which can supported that Bcl-x(L) inhibits cell death at a late (postmitochondrial) step in the death pathway.Identified in a yeast two-hybrid screen,Aven inhibited the proteolytic activation of caspases in a cell-free extract and suppressed apoptosis induced by Apaf-1 plus caspase-9. Expressing highly in the testis, ovary, and thymus . |
| Supplier | Elabscience |
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