| Product Name | AY-NH2 |
|---|---|
| Description | AY-NH2, also known as AYPGKF-NH2, is a selective PAR4 receptor agonist peptide. AY-NH2 stimulates platelet aggregation in vitro with an EC50 of 15 μM and can cause an increase in paw thickness in the paw edema inflammation model. |
| Synonyms | AYPGKF-NH2 |
| Molecular Weight | 680.8 Da |
| Target | Protease activated receptors |
| Amino Acid Sequence | AYPGKF-NH2 |
| Form | Freeze dried solid |
| Purity | >95% by hplc |
| Cas Number | 352017-71-1 |
| Storage | Store dry, frozen and in the dark |
| Notes | Modifications: C-terminal amide |
| References |
Faruqi et al (2000) Structure-function analysis of protease-activated receptor 4 tethered ligand peptides. J.Biol.Chem. 275 19728 PMID: 10779527Palygin et al (2016), Protease€activated Receptor€1€driven Intracellular Calcium Dynamics in Rat Glomerular Podocytes. FASEB J. 30 968.25 PMID: 27733370Meyer et al (2020) Platelet Interactions with Liver Sinusoidal Endothelial Cells and Hepatic Stellate Cells Lead to Hepatocyte Proliferation. Cells 9(5) 1243 PMID: 32443494 Related dataAll peptides >All protease activated receptors >All immunology research categories > |
| Supplier | Isca Biochemicals Limited |
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