| Product Name | B-Myb Polyclonal Antibody |
|---|---|
| Description | MYBL2 encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.MYBL2 (MYB Proto-Oncogene Like 2) is a Protein Coding gene. Diseases associated with MYBL2 include Paraneoplastic Cerebellar Degeneration. Among its related pathways are Cell cycle Cell cycle (generic schema) and HTLV-I infection. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is MYBL1. |
| Synonyms | MYBL2, BMYB, Myb-related protein B, B-Myb, Myb-like protein 2 |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from human B-Myb around the non-phosphorylation site of Ser577. |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IF, WB |
| Form | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Uniprot | P10244 |
| Background | MYBL2 encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene.MYBL2 (MYB Proto-Oncogene Like 2) is a Protein Coding gene. Diseases associated with MYBL2 include Paraneoplastic Cerebellar Degeneration. Among its related pathways are Cell cycle Cell cycle (generic schema) and HTLV-I infection. GO annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is MYBL1. |
| Supplier | Elabscience |
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