| Product Name | B9D1, 1-204aa, Human (Denatured) |
|---|---|
| Description | BpD1 is a B9 domain-containing protein, one of several that are involved in ciliogenesis. Alterations in expression of this gene have been found in a family with Meckel syndrome. Meckel syndrome has been associated with at least six different genes. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Three alternatively spliced transcript variants that encode different proteins have been described for this gene. Recombinant human B9D1 protein, used to His-tag at N-terminus, was expressed in E.coli. |
| Synonyms | B9 domain-containing protein 1 isoform b, B9, EPPB9, MKS9, MKSR1 |
| Host | E. coli |
| Molecular Weight | 44.5kDa (382aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMATASPS VFLLMVNGQV ESAQFPEYDD LYCKYCFVYG QDWAPTAGLE EGISQITSKS QDVRQALVWN FPIDVTFKST NPYGWPQIVL SVYGPDVFGN DVVRGYGAVH VPFSPGRHKR TIPMFVPEST SKLQKFTSWF MGRRPEYTDP KVVAQGEGRE VTRVRSQGFV TLLFNVVTKD MRKLGYDTGP SDTQGVLGPS PPQSFPQ |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M uREA, 10% glycerol |
| Concentration | 0.5mg/ml (determined by Bradford assay) |
| Purity | > 85% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Hopp K., et al (2011). Hum. Mol. Genet. 20:2524-2534 Bialas N.J., et al (2009). J. Cell Sci. 122:611-624 |
| Background | BpD1 is a B9 domain-containing protein, one of several that are involved in ciliogenesis. Alterations in expression of this gene have been found in a family with Meckel syndrome. Meckel syndrome has been associated with at least six different genes. This gene is located within the Smith-Magenis syndrome region on chromosome 17. Three alternatively spliced transcript variants that encode different proteins have been described for this gene. Recombinant human B9D1 protein, used to His-tag at N-terminus, was expressed in E.coli. |
| Supplier | ARP |
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