| Product Name | Bac2A |
|---|---|
| Description | Bac2A is a 12-mer linear variant of the naturally occurring bovine host defense peptide bactenecin. Bac2A has the cysteine disulfide bond-forming residues of bactenecin replaced by alanine and is active as a broad spectrum antimicrobial activity against gram positive and gram negative bacteria, as well as against the yeast Candida albicans. |
| Synonyms | AM-160, AM160, Bac2A, H-RLARIVVIRVAR-NH2, RLARIVVIRVAR, antimicrobial, bovine host defense peptide bactenecin |
| Molecular Weight | 1420.8 Da |
| Target | Antibacterials,Antifungals |
| Amino Acid Sequence | RLARIVVIRVAR-NH2 |
| Form | Lyophilised solid |
| Purity | >95% by HPLC |
| Storage | Store desiccated, frozen and in the dark |
| Notes | Modifications: C terminal amide |
| References |
Wu and Hancock (1999) Improved Derivatives of Bactenecin, a Cyclic Dodecameric Antimicrobial Cationic Peptide. Antimicrob. Agents Chemother. 43(5) 1274 PMID: 10223951Hilpert et al (2006) Sequence requirements and an optimization strategy for short antimicrobial peptides. Chem. Biol. 13(10) 1101 PMID: 17052614 Related areasAll antibacterials >All antifungals >All antimicrobial peptides >All immunology research categories > |
| Supplier | Isca Biochemicals Limited |
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