| Product Name | BACE1 Polyclonal Antibody |
|---|---|
| Description | Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. |
| Synonyms | ASP2,BACE,HSPC104 |
| Host | Rabbit |
| Immunogen | Recombinant protein of human BACE1 |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, WB |
| Form | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | P56817 |
| Background | Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene. |
| Supplier | Elabscience |
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