BAP1 Antibody

Category: Antibodies
Catalog
CSB-PA985124
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Product Name BAP1 Antibody
Description Rabbit polyclonal antibody to BAP1
Synonyms BAP 1 antibody; Bap1 antibody; BAP1_HUMAN antibody; BRCA 1 associated protein 1 antibody; BRCA1 associated protein 1 antibody; BRCA1 associated protein-1 (ubiquitin carboxy-terminal hydrolase) antibody; BRCA1-associated protein 1 antibody; Cerebral protein 13 antibody; Cerebral protein 6 antibody; DKFZp686N04275 antibody; FLJ35406 antibody; FLJ37180 antibody; HUCEP 13 antibody; Hucep 6 antibody; HUCEP13 antibody; Hucep6 antibody; KIAA0272 antibody; TPDS antibody; Ubiquitin carboxy terminal hydrolase antibody; Ubiquitin carboxyl terminal hydrolase BAP 1 antibody; Ubiquitin carboxyl terminal hydrolase BAP1 antibody; Ubiquitin carboxyl-terminal hydrolase BAP1 antibody; UCHL2 antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Fusion protein of human BAP1
Isotype IgG
Target BAP1
Reactivity Human, Mouse, Rat
Applications ELISA, IHC, WB
Form Liquid
Diluent Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Uniprot Q92560
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background This gene belongs to the ubiquitin C-terminal hydrolase subfamily of deubiquitinating enzymes that are involved in the removal of ubiquitin from proteins. The encoded enzyme binds to the breast cancer type 1 susceptibility protein (BRCA1) via the RING finger domain of the latter and acts as a tumor suppressor. In addition, the enzyme may be involved in regulation of transcription, regulation of cell cycle and growth, response to DNA damage and chromatin dynamics. Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS), which involves increased risk of cancers including malignant mesothelioma, uveal melanoma and cutaneous melanoma
Supplier Cusabio

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