| Product Name | BATF3, 1-127aa Human |
|---|---|
| Description | Basic leucine zipper transcriptional factor ATF-like 3, also known as BATF3, is a 127 amino acid protein that localizes to the nucleus and contains one bZIP domain. Interacting with c-Jun, BATF3 functions as a negative regulator of AP-1-mediated transcription, specifically by heterodimerizing with c-Jun and binding to DNA response elements. Recombinant human BATF3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Synonyms | Basic leucine zipper transcriptional factor ATF-like 3, JDP1, JUNDM1, SNFT |
| Host | E. coli |
| Molecular Weight | 52.2 kDa (451aa) |
| Amino Acid Sequence | MGSSHHHHHH SSGLVPRGSH MGSMSQGLPA AGSVLQRSVA APGNQPQPQP QQQSPEDDDR KVRRREKNRV AAQRSRKKQT QKADKLHEEY ESLEQENTML RREIGKLTEE LKHLTEALKE HEKMCPLLLC PMNFVPVPPR PDPVAGCLPR |
| Tag | His-tag |
| Reactivity | Human |
| Applications | SDS-PAGE |
| Form | Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 0.4M Urea |
| Concentration | 0.25 mg/ml (determined by Bradford assay) |
| Purity | > 90% by SDS-PAGE |
| Storage | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -2°C or -7°C. Avoid repeated freezing and thawing cycles. |
| References | Bower K E., et al. (2002) J Biol Chem. 277: 34967-34977. Hidner K., et al. (2008) Science. 322: 1097-1100. |
| Background | Basic leucine zipper transcriptional factor ATF-like 3, also known as BATF3, is a 127 amino acid protein that localizes to the nucleus and contains one bZIP domain. Interacting with c-Jun, BATF3 functions as a negative regulator of AP-1-mediated transcription, specifically by heterodimerizing with c-Jun and binding to DNA response elements. Recombinant human BATF3 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. |
| Supplier | ARP |
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