| Product Name | BBC3 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to BBC3 |
| Synonyms | BBC 3 antibody; Bbc3 antibody; BBC3_HUMAN antibody; BCL 2 binding component 3 antibody; Bcl-2-binding component 3 antibody; BCL2 binding component 3 antibody; JFY 1 antibody; JFY-1 antibody; JFY1 antibody; p53 up regulated modulator of apoptosis antibody; p53 up-regulated modulator of apoptosis antibody; p53 Upregulated Modulator of Apoptosis antibody; PUMA alpha antibody; PUMA/JFY1 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide of human BBC3 |
| Isotype | IgG |
| Target | BBC3 |
| Reactivity | Human |
| Applications | ELISA, WB |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q9BXH1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | This gene encodes a member of the BCL-2 family of proteins. This family member belongs to the BH3-only pro-apoptotic subclass. The protein cooperates with direct activator proteins to induce mitochondrial outer membrane permeabilization and apoptosis. It can bind to anti-apoptotic Bcl-2 family members to induce mitochondrial dysfunction and caspase activation. Because of its pro-apoptotic role, this gene is a potential drug target for cancer therapy and for tissue injury. Alternative splicing results in multiple transcript variants. |
| Supplier | Cusabio |
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