| Product Name | Bcl-XL Monoclonal Antibody |
|---|---|
| Description | BCL2L1 is a member of he BCL-2 protein family. BCL2L1 is expressed as two distinct isoforms,Bcl-xL and Bcl-xS,and is located at the outer mitochondrial membrane. The Bcl-XL isoform is a 233 amino acid protein,acting as an apoptotic inhibitor. Bcl-XL can forms heterodimers with BAX,BAK or BCL2,and the heterodimerization with BAX does not seem to be required for anti-apoptotic activity. The Bcl-XS isoform is a shorter variant that is 178 amino acids in length and lacks a 63 amino acid region (amino acids 126-188),acting as an apoptotic activator. |
| Synonyms | Apoptosis regulator Bcl X,BCL2L1,Bcl-XL |
| Host | Mouse |
| Clone | 60 |
| Immunogen | Fusion protein of Bcl-XL |
| Isotype | IgG2b |
| Reactivity | Human |
| Applications | ELISA, IF, IHC, WB |
| Form | PBS with 0.02% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | Q07817 |
| Background | BCL2L1 is a member of he BCL-2 protein family. BCL2L1 is expressed as two distinct isoforms,Bcl-xL and Bcl-xS,and is located at the outer mitochondrial membrane. The Bcl-XL isoform is a 233 amino acid protein,acting as an apoptotic inhibitor. Bcl-XL can forms heterodimers with BAX,BAK or BCL2,and the heterodimerization with BAX does not seem to be required for anti-apoptotic activity. The Bcl-XS isoform is a shorter variant that is 178 amino acids in length and lacks a 63 amino acid region (amino acids 126-188),acting as an apoptotic activator. |
| Supplier | Elabscience |
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