| Product Name | BCL2L12 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to BCL2L12 |
| Synonyms | B2L12_HUMAN antibody; BCL 2 like 12 (proline rich) antibody; BCL 2 like 12 antibody; BCL 2 like 12 isoform 1 antibody; Bcl 2 like 12 protein antibody; Bcl 2 related proline rich protein antibody; Bcl-2-like protein 12 antibody; Bcl-2-related proline-rich protein antibody; BCL2 like 12 (proline rich) antibody; BCL2 like 12 antibody; BCL2 like 12 isoform 1 antibody; Bcl2 like 12 protein antibody; Bcl2 related proline rich protein antibody; Bcl2-L-12 antibody; BCL2L12 antibody; BPR antibody; MGC120313 antibody; MGC120314 antibody; MGC120315 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Synthesized peptide derived from internal of human BCL2L12. |
| Isotype | IgG |
| Target | BCL2L12 |
| Reactivity | Human, Mouse |
| Applications | ELISA, WB |
| Form | liquid |
| Diluent Buffer | Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Uniprot | Q9HB09 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background |
This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. Scorilas A., Genomics 72:217-221(2001) [PubMed: 11401436]. Hillman R.T., Genome Biol. 5:R8.1-R8.16(2004) [PubMed: 14759258]. Olsen J.V., Cell 127:635-648(2006) [PubMed: 17081983]. |
| Supplier | Cusabio |
All Research Products are sold for laboratory RESEARCH USE ONLY and ARE NOT TO BE USED FOR HUMAN OR ANIMAL THERAPEUTIC OR DIAGNOSTIC APPLICATIONS. The information presented is believed to be accurate; however, said information and products are offered without warranty or guarantee since the ultimate conditions of use and the variability of the materials treated are beyond our control. Nothing disclosed herein is to be construed as a recommendation to use our products in violation of any patents. ARP American Research Products, Inc. does not submit its products for regulatory review by any government body or other organization, and we do not validate them for clinical, therapeutic or diagnostic use, or for safety and effectiveness. You are solely responsible for making sure that the way you use the products complies with applicable laws, regulations and governmental policies and for obtaining all necessary approvals, intellectual property rights, licenses and permissions that you may need related to your use. Under no circumstances shall ARP American Research Products, Inc. be liable for damages, whether consequential, compensatory, incidental or special, strict liability or negligence, breach of warranty or any other theory arising out of the use of the products available from ARP American Research Products, Inc. Nothing contained herein warrants that the use of the products will not infringe on the claims of any patents covering the product itself or the use thereof in combination with other products or in the operation of any process. ARP American Research Products, Inc. disclaims any and all representations or warranties of any kind whatsoever, express or implied, including without limitation any implied warranties of merchantability or fitness for a particular purpose, of non-infringement, or regarding results obtained through the use of any product, whether arising from a statute or otherwise in law or from a course of performance, dealing or usage of trade.