BCL2L2, 1-172aa, Human

Proteins, Recombinant
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Product Name BCL2L2, 1-172aa, Human
Applications SDS-PAGE
Background BCL2-like protein 2, also known as BCL2L2, is a member of the Bcl-2 family of proteins that regulates outer mitochondrial membrane permeability. BCL2L2 is an anti apoptotic member that prevents release of cytochrome c from the mitochondria intermembrane space into the cytosol. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. It is required for normal sperm maturation. Recombinant human BCL2L2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
Concentration 0.5 mg/ml (determined by Bradford assay)
Form Liquid, in 20mM Tris-HCl buffer (pH 8.0) containing 10% glycerol, 1mM DTT, 0.1 M NaCl.
Species Human
Host E.coli
Intended Use For Research Use Only
Molecular Weight 36.9 kDa (336aa), confirmed by MALDI-TOF.
NCBI Accession # NP_004041
Purity > 95% by SDS-PAGE
References Zhu X., et al. (2004) J Neurochem. 89(5):1233-40.
Kromer G., et al. (1997) Nature Med. 3:614.
Storage Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles.
Synonyms Apoptosis regulator Bcl-W, BCLW, BCL2-like protein 2 Apoptosis regulator BCL W, BCL 2 Like 2, Bcl 2 like 2 protein, Bcl 2L2, bcl w, Bcl2 L2, BCL2 like 2, BCL2 like 2 protein, KIAA0271.
Tag His-tag

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