| Product Name | BEST2 Polyclonal Antibody |
|---|---|
| Description | BEST2 (Bestrophin 2) is a Protein Coding gene. Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Ion channel transport. GO annotations related to this gene include chloride channel activity. An important paralog of this gene is BEST4.This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. |
| Host | Rabbit |
| Immunogen | Synthetic Peptide |
| Isotype | IgG |
| Reactivity | Mouse, Rat |
| Applications | IHC, WB |
| Form | PBS with 0.02% sodium azide and 50% glycerol pH 7.4. |
| Uniprot | Q8NFU1 |
| Background | BEST2 (Bestrophin 2) is a Protein Coding gene. Diseases associated with BEST2 include Vitelliform Macular Dystrophy and Bestrophinopathy. Among its related pathways are Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds and Ion channel transport. GO annotations related to this gene include chloride channel activity. An important paralog of this gene is BEST4.This gene is a member of the bestrophin gene family of anion channels. Bestrophin genes share a similar gene structure with highly conserved exon-intron boundaries, but with distinct 3' ends. Bestrophins are transmembrane proteins that contain a homologous region rich in aromatic residues, including an invariant arg-phe-pro motif. Mutation in one of the family members (bestrophin 1) is associated with vitelliform macular dystrophy. The bestrophin 2 gene is mainly expressed in the retinal pigment epithelium and colon. |
| Supplier | Elabscience |
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