| Product Name | BIN1 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to BIN1 |
| Synonyms | AMPH 2 antibody; AMPH2 antibody; Amphiphysin 2 antibody; Amphiphysin II antibody; Amphiphysin like protein antibody; amphiphysin-like antibody; Amphiphysin-like protein antibody; AMPHL antibody; Bin1 antibody; BIN1_HUMAN antibody; Box Dependant MYC Interacting Protein 1 antibody; Box-dependent myc-interacting protein 1 antibody; Bridging integrator 1 antibody; DKFZp547F068 antibody; MGC10367 antibody; MGC105358 antibody; Myc box dependent interacting protein 1 antibody; Myc box-dependent-interacting protein 1 antibody; SH3P9 antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human BIN1 |
| Isotype | IgG |
| Target | BIN1 |
| Reactivity | Human |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | O00499 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | This gene encodes several isoforms of a nucleocytoplasmic adaptor protein, one of which was initially identified as a MYC-interacting protein with features of a tumor suppressor. Isoforms that are expressed in the central nervous system may be involved in synaptic vesicle endocytosis and may interact with dynamin, synaptojanin, endophilin, and clathrin. Isoforms that are expressed in muscle and ubiquitously expressed isoforms localize to the cytoplasm and nucleus and activate a caspase-independent apoptotic process. Studies in mouse suggest that this gene plays an important role in cardiac muscle development. Alternate splicing of the gene results in ten transcript variants encoding different isoforms. Aberrant splice variants expressed in tumor cell lines have also been described. |
| Supplier | Cusabio |
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