| Product Name | Biotin Anti-Mouse CD122 Antibody [5H4] |
|---|---|
| Description | CD122 is a 70-75 kD IL-2 receptor β chain also known as IL-2Rβ, which is also shared by the IL-15 receptor. It is constitutively expressed by NK cells and at lower levels by T cells, B cells, monocytes, and macrophages. The IL-2Rβ chain can combine with either the common γ subunit (γc, CD132) alone or with the γc subunit and the IL-2Rα subunit (CD25) to generate intermediate or high affinity IL-2 receptor complexes, respectively. CD122 expression levels can be upregulated by activation. The 5H4 antibody does not block IL-2 binding to the IL-2 receptor. CD122 is expressed on murine, but not human, CD8+ Tregs involved in the maintenance of T cell homeostasis. |
| Synonyms |
Interleukin-2 receptor subunit beta, Il2rb, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, CD122 |
| Host | Rat |
| Source | Rat |
| Clonality | Monoclonal |
| Clone | 5H4 |
| Conjugate | Biotin |
| Isotype | Rat IgG2a |
| Reactivity | Mouse |
| Applications | FC |
| Form | PBS with 0.05% Proclin300, 1% BSA |
| Uniprot | P16297 |
| Storage | 4°C |
| Supplier | Assay Genie |
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