BMI1 Antibody

Category: Antibodies
Catalog
CSB-PA288653
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Product Name BMI1 Antibody
Description Rabbit polyclonal antibody to BMI1
Synonyms B lymphoma Mo MLV insertion region (mouse) antibody; B lymphoma Mo MLV insertion region 1 homolog antibody; Bmi 1 antibody; BMI1 antibody; BMI1 polycomb ring finger oncogene antibody; BMI1_HUMAN antibody; Flvi 2/bmi 1 antibody; FLVI2/BMI1 antibody; MGC12685 antibody; Murine leukemia viral (bmi 1) oncogene homolog antibody; Oncogene BMI 1 antibody; PCGF 4 antibody; PCGF4 antibody; Polycomb complex protein BMI 1 antibody; Polycomb complex protein BMI-1 antibody; Polycomb group protein Bmi1 antibody; Polycomb group ring finger 4 antibody; Polycomb group RING finger protein 4 antibody; RING finger protein 51 antibody; RNF 51 antibody; RNF51 antibody
Host Rabbit
Clonality Polyclonal
Conjugate Unconjugated
Immunogen Fusion protein of human BMI1
Isotype IgG
Target BMI1
Reactivity Human, Mouse
Applications ELISA, WB
Form Liquid
Diluent Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Uniprot P35226
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Background BMI1 polycomb ring finger oncogene, also known as BMI1, is a protein which in humans is encoded by the BMI1gene. Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. In the PRC1 complex, it is required to stimulate the E3 ubiquitin-protein ligase activity of RNF2/RING2.
Supplier Cusabio

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