| Product Name | BMP-2 derived peptide |
|---|---|
| Description | BMP-2 derived peptide, also known as bone morphogenetic protein 2 (BMP-2) derived peptide, corresponds to residues 73-92 of the knuckle epitope of BMP-2. BMP-2 derived peptide significantly inhibits the binding of recombinant human BMP-2 to both BMP receptors type IA and type II and also promotes the expression of osteocalcin mRNA and induces ectopic calcification in rat calf muscle. BMP-2 derived peptide may one of the receptor binding sites on BMP-2 and may stimulate bone precursor cells to induce calcification. |
| Synonyms | Bone morphogenetic protein 2 derived peptide |
| Molecular Weight | 2334.76 Da |
| Target | Receptor serine/threonine kinase receptors |
| Amino Acid Sequence | KIPKASSVPTELSAISTLYLGGC-NH2 |
| Form | Freeze dried solid |
| Purity | >95% by HPLC |
| Storage | Store desiccated, frozen and in the dark |
| Notes | Modifications: C terminal amide |
| References |
Saito et al (2003) Activation of osteo-progenitor cells by a novel synthetic peptide derived from the bone morphogenetic protein-2 knuckle epitope. Biochim. Biophys. Acta. 1651(1-2) 60 PMID: 14499589Balakin et al (2019) Quantitative analysis of BMP-2 derived peptide covalently grafted onto oxidized detonation nanodiamonds. Carbon 152 740 ISSN 0008-6223 https://doi.org/10.1016/j.carbon.2019.05.064 Related areasAll peptides >All receptor serine/threonine kinase receptor modulators >All immunology research categories >All stem cell research categories > |
| Supplier | Isca Biochemicals Limited |
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