| Product Name | BMPR2 Antibody |
|---|---|
| Description | Rabbit polyclonal antibody to BMPR2 |
| Synonyms | BMP type II receptor antibody; BMP type-2 receptor antibody; BMPR 2 antibody; BMPR 3 antibody; BMPR II antibody; BMPR-2 antibody; BMPR-II antibody; Bmpr2 antibody; BMPR2_HUMAN antibody; BMPR3 antibody; BMPRII antibody; BMR 2 antibody; BMR2 antibody; Bone morphogenetic protein receptor type 2 antibody; Bone morphogenetic protein receptor type II antibody; Bone morphogenetic protein receptor type-2 antibody; Bone morphogenic protein receptor type II serine threonine kinase antibody; BRK 3 antibody; BRK3 antibody; PPH 1 antibody; PPH1 antibody; Serine threonine kinase type II activin receptor like kinase antibody; T ALK antibody; TALK antibody; Type II activin receptor like kinase antibody |
| Host | Rabbit |
| Clonality | Polyclonal |
| Conjugate | Unconjugated |
| Immunogen | Fusion protein of human BMPR2 |
| Isotype | IgG |
| Target | BMPR2 |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC |
| Form | Liquid |
| Diluent Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Uniprot | Q13873 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Background | This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. |
| Supplier | Cusabio |
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