| Product Name | Bonzo Polyclonal Antibody |
|---|---|
| Description | Bonzo (also designated STRL33.3) and BOB (brother of Bonzo; also designated GRP15) are seven-transmembrane, G protein-coupled receptors that are closely related to chemokine receptor family members. In conjunction with CD4, several chemokine receptors are known to serve as receptors for HIV-1 entry into cells. Bonzo and BOB are utilized by simian immunodeficiency virus (SIV), HIV-2 and M-tropic HIV-1 for cell entry. Bonzo and BOB are both expressed in lymphoid tissues, and BOB is also expressed in colon. |
| Synonyms | CXCR6, BONZO, STRL33, TYMSTR, C-X-C chemokine receptor type 6, CXC-R6, CXCR-6, CDw186, G-protein coupled receptor STRL33, G-protein coupled receptor bonzo, CD186 |
| Host | Rabbit |
| Immunogen | Synthesized peptide derived from the N-terminal region of human Bonzo. |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, IHC, WB |
| Form | PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4 |
| Uniprot | O00574 |
| Background | Bonzo (also designated STRL33.3) and BOB (brother of Bonzo; also designated GRP15) are seven-transmembrane, G protein-coupled receptors that are closely related to chemokine receptor family members. In conjunction with CD4, several chemokine receptors are known to serve as receptors for HIV-1 entry into cells. Bonzo and BOB are utilized by simian immunodeficiency virus (SIV), HIV-2 and M-tropic HIV-1 for cell entry. Bonzo and BOB are both expressed in lymphoid tissues, and BOB is also expressed in colon. |
| Supplier | Elabscience |
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