| Product Name | BRWD1 Polyclonal Antibody |
|---|---|
| Description | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues whicHuman, Mouseay facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain whicHuman, Mouseay regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex. |
| Synonyms | N143,WDR9,C21orf107 |
| Host | Rabbit |
| Immunogen | Synthetic peptide of human BRWD1 |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Applications | ELISA, IHC |
| Form | PBS with 0.05% sodium azide, 50% glycerol, PH7.3 |
| Uniprot | Q9NSI6 |
| Background | This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD) residues whicHuman, Mouseay facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 2 bromodomains and multiple WD repeats. This gene is located within the Down syndrome region-2 on chromosome 21. Alternative splicing of this gene generates multiple transcript variants encoding distinct isoforms. In mouse, this gene encodes a nuclear protein that has a polyglutamine-containing region that functions as a transcriptional activation domain whicHuman, Mouseay regulate chromatin remodelling and associates with a component of the SWI/SNF chromatin remodelling complex. |
| Supplier | Elabscience |
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